John VorhausThe population of the elderly has progressively risen. The demand for anti-aging health products guarantees longevity and ameliorates age-related complications. There are various anti-aging products and NMN gained the attention of the customers and the scientific community. The reduced form nmn has potential benefits, such as:
- NAD+ enhancer
- Glycolysis suppressor
- TCA cycle
- Cell growth
Mitochondria decay is responsible for aging, which is reversible by the increased levels of NAD+ (Nicotinamide Adenine Dinucleotide). NMN is the precursor of NAD+, which acts as the intermediate in NAD+ biosynthesis. The NMN dietary supplements increase the NAD+ level of the human body, It is a proactive nucleotide that formed in the reaction between these two:
- nucleoside comprising nicotinamide
- ribose
- phosphate group
It naturally presents in various plants. Several studies were performed to study the prospect of biotechnological production and filtering NMN from yeasts and bacteria.
Benefits of the reduced form nicotinamide mononucleotide
Enhances NAD+
Enhancing NAD+ levels can have a lot of benefits to the body, such as:
- reduces chronic low-grade inflammation
- reactivates autophagy and mitochondrial biogenesis
- improves oxidative metabolism in vascular cells
Increasing NAD+ levels increases cell defense, which induces DNA repair. So, it can keep you from cancerogenesis and some other diseases. Increasing NAD+ levels helps improve mitochondrial functions that activate mitophagy. NAD+ levels enhance the regeneration of keratinocytes.
The age-dependent dermal accumulation of an oxidatively damaged and modified protein causes skin dysfunction. Therefore, increasing the levels of NAD+ plays an essential role in regaining the younger look of the skin.
Suppresses glycolysis
Glycolytic suppression can reprogram the intracellular energy metabolism to the mitochondrial OXPHOS. The autophagic process can mediate metabolic reprogramming. Thus, the quality control of mitochondria and the supply of amino acids by mitophagy has a huge role.
TCA Cycle
The TCA cycle completes the glucose oxidation to carbon dioxide in the cell, providing an intermediate for the biosynthesis of amino acids. It is the final step for:
- carbohydrate
- fat
- protein catabolism
The TCA cycle is also the main source of ATP production, which plays an essential role in a person’s health
Cell growth
The cells on the skin grow faster as a response to rubbing or pressure. NMN can also have benefits when it comes to cell growth. NMN helps the renewal of cells to regain smoother skin, regain the skin healthier.
The various healthy aging benefits of NMN are:
- better skin health
- increased energy
- potential improvements in thinking skills
- fighting age-related decline
NMN benefits in anti-aging have a great potential for the holistic approach towards aging, promoting better skin health.